Safety of Recombinant Human C1 Esterase Inhibitor for Hereditary Angioedema Attacks in Pregnant Women
نویسندگان
چکیده
منابع مشابه
Recombinant Human C1 Esterase Inhibitor in the Management of Hereditary Angioedema
Hereditary angioedema (HAE), a rare autosomal dominant genetic disorder, is caused by a deficiency in functional C1 esterase inhibitor (C1-INH). This potentially life-threatening condition manifests as recurrent attacks of subcutaneous and submucosal swelling of the skin, gastrointestinal tract and larynx. The management of HAE includes treatment of acute episodes, short-term prophylaxis in pre...
متن کاملSelf-administration of intravenous C1 esterase inhibitor in hereditary angioedema.
somal dominant disorder that results in episodes of acute edema in various organs, including the gastrointestinal tract, skin and larynx. It is estimated to affect about 1 in 50 000–100 000 people. The symptoms, including abdominal pain, laryngeal edema and subcutaneous edema, usually begin in childhood and persist throughout life with unpredictable severity. Hereditary angioedema is classified...
متن کامل85 Clinical Efficacy of Recombinant Human C1 Inhibitor in Patients with Acute Hereditary Angioedema Attacks
84 Immuno-Safety of Recombinant Human C1 Inhibitor in Patients With Hereditary Angioedema: An Integrated Analysis Erik Hack, MD, PhD, Anurag Relan, MD, Leonard Kaufman, PhD, and Rienk Pijpstra, MD. Department of Immunology, Dermatology/Allergology & Reumatology, University Medical Center, Utrecht, Utrecht, Netherlands; Pharming Technologies BV, Leiden, Netherlands; Veeda Clinical Research, Brus...
متن کامل84 Immuno-Safety of Recombinant Human C1 Inhibitor in Patients With Hereditary Angioedema: An Integrated Analysis
84 Immuno-Safety of Recombinant Human C1 Inhibitor in Patients With Hereditary Angioedema: An Integrated Analysis Erik Hack, MD, PhD, Anurag Relan, MD, Leonard Kaufman, PhD, and Rienk Pijpstra, MD. Department of Immunology, Dermatology/Allergology & Reumatology, University Medical Center, Utrecht, Utrecht, Netherlands; Pharming Technologies BV, Leiden, Netherlands; Veeda Clinical Research, Brus...
متن کامل[Hereditary angioedema due to C1-esterase inhibitor deficiency].
The paper presents a case of family oedema by shortage of C1-esterase inhibitor, characterized by appearance at an early age (8 months), participation in some attacks of nasal mucous membrane, with nasal obstruction and sinusal manifestations and also the abnormally long period, up to 9 days, of some localized oedemas. The crises were absent during pregnancy. The study of four generations of th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2018
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2017.12.169